PCOD
The document is a lecture note on Polycystic Ovarian Syndrome (PCOS) by Professor Lanka Dasanayake, a Professor of Obstetrics & Gynaecology at the University of Ruhuna in Sri Lanka. The lecture covers various aspects of PCOS, including its historical description, objectives, symptom presentation, diagnosis definitions, potential causes, metabolic and reproductive complications, infertility, and treatments. It discusses the main symptoms of PCOS, such as polycystic ovaries, hyperandrogenism, and anovulation/oligo-ovulation, as well as additional features like excessive hair growth, hair loss, obesity, and acne. The lecture also highlights the difficulty in diagnosing PCOS and the criteria for diagnosis, including the Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group criteria. It emphasizes the genetic predisposition, aging, pregnancy, drugs, lifestyle, insulin resistance, and altered fat metabolism as potential causes of PCOS. The document also discusses the metabolic disorder associated with PCOS, including insulin resistance, obesity, and the risk factors for endometrial hyperplasia, cardiovascular disease, sleep apnea, and depression. Additionally, it covers pregnancy complications, infertility, weight loss programs, infertility treatments, stimulated cycles, and the multifaceted nature of PCOS, including its long-term consequences, genetic implications, cosmetic issues, and reproductive complications. The lecture concludes by highlighting the commonality of PCOS as an endocrinopathy in pre-menopausal women and the availability of multiple treatments with potentially successful outcomes.